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Submitted: 09 Oct 2016
Accepted: 04 Jan 2017

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Pharm Sci. 2017;23(2):166-169 doi: 10.15171/PS.2017.24

Antibacterial Activity of Anti-Aphthous Spray and Oral Drop: Two Thymus Commercial Products

Short Communication

Mohammadreza Nahaei 1, Parisa Rahbarfam 1, Mahsa Kalajahi 1, Solmaz Maleki Dizaj 2, Farzaneh Lotfipour 2 *

1 Department of Biological Sciences, Tabriz Higher Education Institute of Rab-Rashid, Tabriz, Iran.
2 Faculty of Pharmacy and Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.


Background: Today, traditional medicine is developed globally as an important source for health care of the world's population. The current study describes the antibacterial activity of thymus commercial products against both Gram-positive including Staphylococcus aureus, Streptococcus pyogenes and Gram-negative bacteria including Escherichia coli, Pseudomonas aeruginosa.

Methods: Two commercial products of thymus with standard expiration date (and in three different batch numbers) including anti-aphthous spray and oral drop were purchased from the pharmacies of Tabriz city. Minimum Inhibitory Concentration (MIC) and disk diffusion are used to investigate the antibacterial efficiency of the mentioned products.

Results: The results of disk diffusion method showed zones of growth inhibition against S. aureus and S. pyogenes for the investigated products. Based on MICs, thymus oral drop had inhibitory effects against S. aureus, S. pyogenes while anti-aphthous spray showed inhibitory effects against S. aureus, S. pyogenes and P. aeruginosa. The findings also indicated that the thymus anti-aphthous spray had more inhibitory effects than thymus oral drop.

Conclusion: This study showed that thymus can be used as an optimistic antibacterial agent against the selected microorganisms.

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Articles by Nahaei M
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Articles by Nahaei M
Articles by Rahbarfam P
Articles by Kalajahi M
Articles by Maleki Dizaj S
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