Tabriz University of Medical Sciences About    Newsletter    Contact Us    Create Account    Log in  
Journal of Analytical Research in Clinical Medicine
   eISSN: 2345-4970  
Export citation
Reference Manager

Cite by
Google Scholar

Article History
Submitted: 23 May 2017
Revised: 30 Jun 2017
Accepted: 01 Jul 2017
First published online: 01 Jul 2017

Article Access Statistics
Abstract Page Views: 387
PDF Downloads: 697
Full Text Views: 0

J Anal Res Clin Med. 2017;5(3):86-90 doi: 10.15171/jarcm.2017.017

Role of Helicobacter Pylori stool antigen test in the diagnosis of Helicobacter Pylori infection

Original Article

Tala Pourlak 1, Behrooz Shokouhi 1 * , Amir Vahedi 1

1 Department of Pathology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

Introduction: Helicobacter pylori (H. pylori) infection is common in developing countries. There are various invasive and non-invasive methods for diagnosing H. pylori infection. Stool antigen test is a new non-invasive method to diagnose H. pylori infection. In this study we evaluated the diagnostic accuracy of HpSA for H. pylori infection in patients with gastrointestinal (GI) complaints. Methods: Sixty patients including 28 men and 32 women with mean age of 49.2 ± 19.8 years undergoing diagnostic endoscopy with 30 positive and 30 negative rapid urease test (RUT) and histology results for H. pylori infection were evaluated. H. pylori stool antigen test (HpSA) was measured in these patients and sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy for HpSA were calculated. Results: Among 31 positive HpSA results, 2 were negative in RUT and histology and among 29 negative HpSA results, 1 was positive in RUT and histology results. Sensitivity, specificity, PPV, NPV and accuracy for HpSA in diagnosing H. pylori infection were 96.67%, 93.33%, 93.55%, 96.55% and 95%, respectively. Conclusion: Although the sensitivity and specificity of the HpSA are evaluated in a relatively small sample size, these results showed that HpSA is a useful test in diagnosing H. pylori infection in patients with upper GI complaints.

First name  
Last name  
Email address  
Security code

This Article

Google Scholar
Articles by Pourlak T
Articles by Shokouhi B
Articles by Vahedi A

Articles by Pourlak T
Articles by Shokouhi B
Articles by Vahedi A

Share this article!
© 2017 Tabriz University of Medical Sciences; unless otherwise stated.

Press Manuscript Online. Powered by MAADRAYAN