Pharm Sci. 2016;22(4):285-290 doi: 10.15171/PS.2016.44
the Antibacterial Effects of Two Commercial Products of Eucalyptus globulus
Against Common Microbial Causes of Respiratory Tract Infections
Background: Recently, antimicrobial activity of medicinal
plants have attained once more importance due to drug resistance of
microbial isolates to common antibiotics as well as fewer side effects and low
cost of herbal products comparing to chemical drugs. Eucalyptus globules
(E. globulus) has been widely applied as a natural remedy in respiratory
tract infections. The present study focused on the evaluation of antibacterial
effect of two commercial products of E. globulus against common
microbial causes of respiratory tract infections. To this end, two
commercial products of E. globules including inhaler and oral soft
capsule with standard expiration date, (in three different batch numbers) were
purchased from the pharmacy stores of Tabriz city.
Methods: The antibacterial efficiency of these products were
investigated using Minimum Inhibitory Concentration (MIC), Minimum
Bactericidal Concentration (MBC) and disk diffusion methods against Staphylococcus
aureus, Streptococcus pyogenes and Pseudomona aeruginosa.
Results: Based on the obtained results, these commercial
products of E. globules showed significant inhibitory effects against
Gram-positive bacteria. The findings also indicated that the Eucalyptus inhaler
products had more inhibitory effects than Eucalyptus oral soft capsule,
however batch to batch variations were of concern.
Conclusion: This research
presents optimistic result on using the Eucalyptus as an alternative
antibacterial agent against respiratory
tract pathogenic microorganisms.