Tabriz University of Medical Sciences About    Newsletter    Contact Us    Create Account    Log in  

ISSN: 1735-403X      eISSN: 2383-2886  
Export citation
Reference Manager

Cite by
Google Scholar

Article History
Submitted: 20 Nov 2016
Accepted: 23 Jan 2017

Article Access Statistics
Abstract Page Views: 401
PDF Downloads: 492
Full Text Views: 0

Pharm Sci. 2017;23(2):136-142 doi: 10.15171/PS.2017.20

Evaluation of the Phytochemical and Antioxidant Potential of Aerial Parts of Iranian Tanacetum parthenium

Research Article

Farshid Rezaei 1, Rashid Jamei 1 * , Reza Heidari 1

1 Department of Biology, Faculty of Science, University of Urmia, Urmia, Iran.


Background: The objective of this study was to analyze the essential oil, fatty acid, flavonoid, phenolic compounds and in vitro antioxidant activity of oil from Feverfew (Tanacetum parthenium L.) wild grown and collected from north of Iran.

Methods: The essential oil of aerial parts was analyzed by spectroscopy method (GC/MS using HP-5MS column) while the fatty acid content was analyzed by gas chromatography (GC/FID). Phenolic contents of the oil were evaluated using high performance liquid chromatography (HPLC/UV) technique while total phenols and flavonoids were determined colorimetrically. The in vitro antioxidant activity of the essential oil was evaluated by 1,1-diphenyl-2 picryl hydrazyl (DPPH) radical scavenging technique.

Results: In the essential oil thirteen compounds were characterized with camphor (43.97 %), chrysanthenyl acetate (12.46 %) and farnesol (7.54%) as the major components. Principal fatty acid components of the herb were palmitic acid (57.27%) and myristic acid (14.7%). HPLC analysis revealed that the cinnamic acid derivatives were the major compounds, with sinapic (3.86 ± 0.1 mg/g dw) and ferulic (2.59 ± 0.1 mg/g dw) acids being the predominant ones. Also, evaluation the bioactivity of the oil showed considerable antioxidant capacity (TPC = 152.8 ± 0.8 mg/g and DPPH = 73.8 ± 1.3 %).

Conclusion: This study revealed that the essential oil was rich in camphor/chrysanthenyl acetate chemotype and different polyphenols in the category of hydroxycinnamic acid derivatives. In addition, this research demonstrated that the aerial parts of this aromatic herb were various sources of oily components, especially essential fatty acids.

First name  
Last name  
Email address  
Security code

This Article

Google Scholar
Articles by Rezaei F
Articles by Jamei R
Articles by Heidari R

Articles by Rezaei F
Articles by Jamei R
Articles by Heidari R

Share this article!
© 2016 Tabriz University of Medical Sciences; unless otherwise stated
Press Manuscript Online. Powered by MAADRAYAN