Logo-jrcm
J Anal Res Clin Med. 2016;4(4): 233-237.
doi: 10.15171/jarcm.2016.039
  Abstract View: 1452
  PDF Download: 1041

Case Report

A Case of Solitary Neurofibroma in Outer Surface of Nose

Shahin Abdollahi-Fakhim 1, Saman Rezaeian 2, Hojjat Hosseinpour-Feizi 3, Mohammad Naghavi-Behzad 4, Reza Piri 5*

1 Associate Professor, Department of Ear, Nose and Throat (ENT), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2 Resident, Department of Ear, Nose and Throat (ENT), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
3 Associate Professor, Department of Orthopedics Surgery, Shohada Educational Medical Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
4 Student of Medicine, Students’ Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
5 Student of Medicine, Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
*Corresponding Author: Email: reza.piri@rocketmail.com

Abstract

Solitary neurofibroma is a benign tumor originating from Schwann cells in peripheral nerves. In an investigation of 430000 pathologic samples, only 6 cases of neurofibroma had been reported in nose and paranasal sinuses. Present patient was a 15-year-old girl with left-sided nasal and malar mass, whose CT scan and MRI showed a non-circumscribed solid mass with total thickness affecting outer part of nose in left side as well as surface and deep soft tissue. The mentioned mass underwent excision by sub-labial incision and open rhinoplasty keeping infra-orbit nerve intact. Pathologic investigation of samples showed adipose fibroblast and skeletal muscle fibers with proliferation of spindle-shaped cells and staining was negative for GFAP and positive for S-100 which represents diagnosis of neurofibroma. Main differential diagnoses of benign tumors of paranasal sinuses and nasal cavity include neurofibroma, fibroma, leiomyomas, papilloma, and schwannoma. After resection tumor should be precisely monitored, since there is malignant transformation possibility in solitary neurofibromas.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 1453

Your browser does not support the canvas element.


PDF Download: 1041

Your browser does not support the canvas element.

Submitted: 20 May 2016
Accepted: 18 Jun 2016
ePublished: 06 Aug 2016
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)