Tabriz University of Medical Sciences About    Newsletter    Contact Us    Create Account    Log in  
Advanced Pharmaceutical Bulletin
ISSN: 2228-5881      eISSN: 2251-7308  
Services
Export citation
EndNote
Reference Manager
BibTeX
Medlars
Refworks
Mendeley

Cite by
Google Scholar
PMC(0)


Article History
Submitted: 10 Apr 2013
Revised: 15 May 2013
First published online: 24 Dec 2013

Article Access Statistics
Abstract Page Views: 226
PDF Downloads: 141
Full Text Views: 0

Adv Pharm Bull. 2014;4(2):101-104 doi: 10.5681/apb.2014.016
PMID:24511472        PMCID:PMC3915808

Synthesis, Characterization and Antioxidant Property of Quercetin-Tb(III) Complex

Original Research

Jafar Ezzati Nazhad Dolatabadi 1, Ahad Mokhtarzadeh 2, Seyed Morteza Ghareghoran 1, Gholamreza Dehghan 3 *

1 Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.
2 Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
3 Department of Plant Biology, Faculty of Natural Science, University of Tabriz, Tabriz, Iran.



Abstract
Purpose: Nearly all of flavonoids are good metal chelators and can chelate many metal ions to form different complexes. This article describes a synthesis of Quercetin–Tb(III) in methanol, characterized by using elemental analysis, UV–visible and evaluation of its antioxidant properties.Methods: The formation of complexes is realized from the UV–visible spectra which shows that the successive formation of Quercetin–Tb(III) occurs. To find out the antioxidant activity variation and the role of Tb(III) ion on the antioxidant activity of the complexes different radical scavenging methods such as: 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and 2,2′-azinobis 3-ethylbenzothiazoline-6-sulphonic acid (ABTS) were used.Results: The results from DPPH, ABTS and FRAP methods showed that Quercetin and Quercetin–Tb(III) complex are capable of donating electron or hydrogen atom, and consequently could react with free radicals or terminate chain reactions in a time- and dose-dependent manner.Conclusion: This study showed that the chelation of metal ions by Quercetin decrease the redox potential of Quercetin-metal complex.





Comments
First name  
Last name  
Email address  
Comments  
Security code



This Article
PDF

Google Scholar
Articles by Ezzati Nazhad Dolatabadi J
Articles by Mokhtarzadeh A
Articles by Ghareghoran SM
Articles by Dehghan G

PubMed
Articles by Ezzati Nazhad Dolatabadi J
Articles by Mokhtarzadeh A
Articles by Ghareghoran SM
Articles by Dehghan G

Similar articles in PubMed

Share this article!

Press Manuscript Online. Powered by MAADRAYAN