Tabriz University of Medical Sciences About    Newsletter    Contact Us    Create Account    Log in  
Advanced Pharmaceutical Bulletin
ISSN: 2228-5881      eISSN: 2251-7308  
Services
Export citation
EndNote
Reference Manager
BibTeX
Medlars
Refworks
Mendeley

Cite by
Google Scholar
PMC(0)


Article History
Submitted: 07 Apr 2014
Revised: 22 Jun 2014
Accepted: 02 Jul 2014
First published online: 31 Dec 2015

Article Access Statistics
Abstract Page Views: 390
PDF Downloads: 163
Full Text Views: 0

Adv Pharm Bull. 2015;5(5):599-603 doi: 10.15171/apb.2015.081
PMID:26793604        PMCID:PMC4708029

New Approaches to the Immunotherapy of Type 1 Diabetes Mellitus Using Interleukin-27

Editorial

Fatemeh Zamani 1,2, Shohreh Almasi 1,2, Tohid Kazemi 1,2, Rana Jahanban Esfahlan 3, Mohammad Reza Aliparasti 4 *

1 Immunology Research Center (IRC), Tabriz University of Medical Sciences, Tabriz, Iran.
2 Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
3 Department of Medical Biotechnology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
4 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.



Abstract
Type 1 diabetes (T1D) is a pancreatic beta cell specific autoimmune disease. One of the most significant current discussions in T1D studies is therapy. Since the conventional therapy, islet transplantation and external insulin, e.g., cannot prevent the destructive autoimmune process against original beta cells and persistent hyperglycemia remains, so recent developments in the field of T1D therapy paved the way to a renewed interest in immunotherapy based on the disease process, especially monoclonal antibody therapy. Due to encouraging laboratory results, cytokine antibody-based drugs could be effective in the clinical direction of the T1D disease process. Hence, implementation of this approach can be useful to improve clinical and laboratory manifestations of T1D.





Comments
First name  
Last name  
Email address  
Comments  
Security code



This Article
PDF

Google Scholar
Articles by Zamani F
Articles by Almasi S
Articles by Kazemi T
Articles by Jahanban Esfahlan R
Articles by Aliparasti MR

PubMed
Articles by Zamani F
Articles by Almasi S
Articles by Kazemi T
Articles by Jahanban Esfahlan R
Articles by Aliparasti MR

Similar articles in PubMed

Share this article!

Press Manuscript Online. Powered by MAADRAYAN