Tabriz University of Medical Sciences About    Newsletter    Contact Us    Create Account    Log in  
Advanced Pharmaceutical Bulletin
ISSN: 2228-5881      eISSN: 2251-7308  
Services
Export citation
EndNote
Reference Manager
BibTeX
Medlars
Refworks
Mendeley

Cite by
Google Scholar



Article History
Submitted: 03 Jul 2016
Revised: 10 Mar 2017
Accepted: 04 Apr 2017
First published online: 13 Apr 2017

Article Access Statistics
Abstract Page Views: 132
PDF Downloads: 100
Full Text Views: 0

Adv Pharm Bull. 2017;7(1):151-157 doi: 10.15171/apb.2017.019

Voltammetric Determination of Ivabradine Hydrochloride Using Multiwalled Carbon Nanotubes Modified Electrode in Presence of Sodium Dodecyl Sulfate

Research Article

Ali Kamal Attia 1 * , Nisreen Farouk Abo-Talib 1, Marwa Hosny Tammam 1

1 National Organization for Drug Control and Research, P.O. Box 29, Cairo, Egypt.



Abstract

Purpose: A new sensitive sensor was fabricated for the determination of ivabradine hydrochloride (IH) based on modification with multiwalled carbon nanotubes using sodium dodecyl sulfate as micellar medium to increase the sensitivity.

Methods: The electrochemical behavior of IH was studied in Britton-Robinson buffer (pH: 2.0-11.0) using cyclic and differential pulse voltammetry.

Results: The voltammetric response was linear over the range of 3.984 x 10-6-3.475 x 10-5 mol L-1. The limits of detection and quantification were found to be 5.160 x 10-7 and 1.720 x 10-6 mol L-1, respectively.

Conclusion: This method is suitable for determination of IH in tablets and plasma.







Comments
First name  
Last name  
Email address  
Comments  
Security code



This Article
PDF

Google Scholar
Articles by Attia AK
Articles by Abo-Talib NF
Articles by Tammam MH

PubMed
Articles by Attia AK
Articles by Abo-Talib NF
Articles by Tammam MH



Share this article!

Press Manuscript Online. Powered by MAADRAYAN