Tabriz University of Medical Sciences About    Newsletter    Contact Us    Create Account    Log in  
Advanced Pharmaceutical Bulletin
ISSN: 2228-5881      eISSN: 2251-7308  
Export citation
Reference Manager

Cite by
Google Scholar

Article History
Submitted: 10 Feb 2016
Revised: 17 Mar 2016
Accepted: 02 Apr 2016
First published online: 29 Jun 2016

Article Access Statistics
Abstract Page Views: 444
PDF Downloads: 344
Full Text Views: 0

Adv Pharm Bull. 2016;6(2):163-169 doi: 10.15171/apb.2016.023

Essential Oil from Flowers and Leaves of Elaeagnus Angustifolia (Elaeagnaceae): Composition, Radical Scavenging and General Toxicity Activities

Research Article

Mohammadali Torbati 1, Solmaz Asnaashari 2, Fariba Heshmati Afshar 3 *

1 Department of Food Science and Technology, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.
2 Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
3 Department of Pharmacognosy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.


Purpose: The aim of this work was to identify the chemical composition of the essential oils obtained from the flowers and leaves of Elaeagnus angostifolia (Elaeagnaceae) along with evaluate the radical scavenging and general toxicity activities.

Methods: A combination of GC-MS and GC-FID were utilized for analyzing the chemical profile of the essential oils extracted by hydro-distillation from the leaves and flowers of E. angustifolia. The essential oils were subjected to general toxicity and radical scavenging assays using brine shrimp lethality test and DPPH method, respectively.

Results: In total, 53 and 25 components were identified and quantified in the essential oils of flowers and leaves, accounting for 96.59% and 98.97% of the oil, respectively. The both oils were observed to be rich in ester compounds. The most abundant components of the oil from flowers were E-ethyl cinnamate (60.00%), hexahydrofarnesyl acetone (9.99%), palmitic acid (5.20%) and phytol (3.29%). The major constituents of the oil from leaves were E-ethyl cinnamate (37.27%), phytol (12.08%), nonanal (10.74%) and Z-3-hexenyl benzoate (7.65%). Both oils showed moderate activity in DPPH assay; however, they exhibited potent tocixity in brine shrimp lethality test.

Conclusion: The remarkable toxicity effects of the oils are worthy to further investigation to find the probable mechanisms of action accountable for the noticeable toxic effect of these essential oils.

First name  
Last name  
Email address  
Security code

This Article

Google Scholar
Articles by Torbati M
Articles by Asnaashari S
Articles by Heshmati Afshar F

Articles by Torbati M
Articles by Asnaashari S
Articles by Heshmati Afshar F

Share this article!

Press Manuscript Online. Powered by MAADRAYAN