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Advanced Pharmaceutical Bulletin
ISSN: 2228-5881      eISSN: 2251-7308  
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Submitted: 20 Apr 2013
Revised: 15 May 2013
First published online: 20 Aug 2013

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Adv Pharm Bull. 2013;3(2):429-432 doi: 10.5681/apb.2013.069
PMID:24312872        PMCID:PMC3848206

Characterization of Non-Terpenoids in Marrubium crassidens Boiss. Essential Oil

Original Research

Sanaz Hamedeyazdan, Solmaz Asnaashari, Fatemeh Fathiazad *

Purpose: Marrubium crassidens, a plant belonging to the family Lamiaceae, was studied for its volatile components present in the aerial parts of the plant during the flowering stage. Methods: The essential oil of the plant obtained through hydrodistillation of the dried plant material was assessed for its chemical composition by GC/MS and GC-FID analyses. Results: Twenty-five compounds were identified, which constituted 94.3% of the total oil composition. The major components were identified as, m-tolualdehyde (23.3%), acetophenone (15.8%), nonacosane (13.1%), docosane (7.2%), o-tolualdehyde (4.1%), β-caryophyllene (3.8%) and caryophyllene oxide (3.4%). Non-terpenoids with 75.7% were the most abundant components of the essential oil. Conclusion: Overall, M. crassidens essential oil revealed to include rather higher proportions of non-terpenoid compounds compared with other species of genus Marrubium.

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