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Advanced Pharmaceutical Bulletin
ISSN: 2228-5881      eISSN: 2251-7308  
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Article History
Submitted: 14 Jul 2012
Revised: 25 Aug 2012
First published online: 07 Feb 2013

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Adv Pharm Bull. 2013;3(1):247-248 doi: 10.5681/apb.2013.040
PMID:24312843        PMCID:PMC3846056

Skin Infection Management Using Novel Antibacterial Agents

Commentary

Ramin Mohammadzadeh * , Nejla Ahmadiyan


Abstract
Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA) cause difficulties in the management of skin and soft tissue infections and have led to morbidity and mortality in hospital-acquired infections especially in susceptible individuals, those who are generally sick or immunosuppressed. Currently approaches in antibacterial agents offer opportunities to manage the trouble using novel anti-infection systems. Therefore, nanotechnology, a most promising field for generating new applications in medicine, has introduced a most prominent nanoproduct named as nanosilver that revealed excellent antimicrobial activity against some of the hazardous infections. Also cathelicidin peptides which are a part of native immune defense system in the skin and epithelia exhibit excellent antimicrobial activity against some of these perilous infections.





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